Tazarotene uk is a topical medication that works for psoriasis, acne, and wrinkles caused by sun damage. It is in a class of medications called retinoids. It has a structure similar to Vitamin A and is thought to work by affecting how skin cells grow and renew themselves. It can also affect the genes that control these processes.
Usually, this medicine is applied once daily. The exact time of application will vary depending on the condition being treated and the doctor’s instructions. It should be applied after the skin has been washed and is dry. It is important to follow the doctor’s instructions exactly for applying this medicine.
Some people may experience irritation in and around the areas where the cream is used. If this happens, the doctor may recommend using the cream less often or changing to another brand of this medicine. In severe cases, the doctor may advise patients to stop the medication and use other products for skin care, such as moisturizers.
The exact way that tazarotene uk works is not fully understood, but it is thought to reduce the excessive cell growth and keratinisation (process by which skin cells form thick layers) seen in psoriasis. It can also help to reduce the flaking and scaling of the skin. It is a type of medication known as a retinoid and has a structure that is similar to Vitamin A.
It is thought that tazarotene works by binding to the retinoic acid receptors and altering how they control gene expression. The active metabolite of this drug, tazarotenic acid, binds selectively to the RAR b and RXR a subtypes of the retinoic acid receptor. These alterations are thought to lead to reduced inflammation and other cellular effects.
The most common side effect of this medication is skin irritation. This can be mild, moderate, or severe. It may start right after you begin using the medication and get worse over time. You may also develop other side effects, such as itching, redness, blotchiness, and swelling. These side effects are most likely to happen when you first start using this medication.
This medication should not be used by people who are allergic to it or to other tazarotene products, such as gels and foams. It is also not recommended for pregnant women. It has not been studied to see if this medication is safe for use during breastfeeding. If you are pregnant or breastfeeding, talk to your doctor before using this medication.
Tazarotene uk is absorbed through the skin and is then distributed throughout the body. It is mostly excreted in the urine, with some faeces as well. The drug is also absorbed in small amounts through the oral mucosa, but is not a significant route of administration.
This document is part of a series of monographs that evaluate drugs for inclusion in the VA National Formulary. This document is updated as new clinical data warrant additional formulary discussion. It is intended to aid pharmacists in making a rational drug selection for individual patients. tazarotene uk